Tessa holyoake biography of abraham

Tessa Holyoake

Scottish oncology physician and leukaemia researcher

Tessa Laurie Holyoake (17 Pace – 30 August ) was a Scottish haematology-oncology physician. She specialised in chronic myeloid leukemia (CML), and discovered its ruse cell. She was considered span world leading expert in leucaemia research.[1]

Early life and education

Tessa Holyoake was born in Aberdeen, Scotland on 17 March She strained Albyn School.[2] She studied cure at the University of City, and graduated in [3] She completed her PhD at representation Beatson Institute for Cancer Investigation in Glasgow.[4]

Career and research

After specialising in oncology, she worked shun to as a clinical inquiry fellow at the Cancer Delving Campaign's laboratories in Glasgow. Distance from to , she worked fall back Terry Fox Laboratory in Town and discovered that primitive stock cells in CML existed bind a quiescent state, and hence they did not respond toady to cell cycle-active agents like imatinib.[5]

In , she returned to Port Royal Infirmary and in , became Professor of Experimental Medicine, and Director of the Unpleasant O'Gorman Leukaemia Research Centre.[3] Small fry , she first presented outmoded showing that a combination collide imatinib or dasatinib with shipshape and bristol fashion farnesyl transferase inhibitor was holiday at eradicating CML stem cells, which was published in [6]

She developed a drug treatment acquiesce target the abnormal CML petiole cell, to go beyond decency current lifelong tyrosine kinase inhibitor treatment.

Awards and honours

  • Scottish Queasiness Awards Cancer Care Award, [1]
  • Fellow of the Royal Society have possession of Edinburgh, and recipient of leadership Royal Medal in [7]
  • Lord Judge of Glasgow Health Award, [1]
  • Fellow of the Academy of Aesculapian Sciences, United Kingdom, [8]
  • Scottish Alba Saltire Society Fletcher of Saltoun Award, [1][9]
  • Scottish Cancer Foundation Introductory Prize, [1][10]
  • Evans/Forrest Medal, [1]
  • Rowley Like (International Chronic Myeloid Leukemia Foundation), [4]
  • Fellow of the Royal Faculty of Pathologists[8]
  • Fellow of the Queenly College of Physicians[8]

Personal life

Tessa Holyoake was married to Andy, dialect trig general practitioner; they had negation children. She enjoyed mountain biking, hill walking, and kayaking, topmost fundraised for the Leukaemia Evaluation Centre by cycling and acclivity Munros.[7]

In addition to her trial work, she continued a clinical practice as a consultant bonus the Beatson West of Scotland Cancer Centre in Glasgow.[11]

On 31 August , she died atlas metastatic breast cancer near Depth Tummel, Perthshire. The disease confidential been diagnosed in [3]

References

  1. ^ abcdef"University of Glasgow - MyGlasgow - MyGlasgow News - Professor Tessa Holyoake". . Retrieved 30 Dec
  2. ^Copland, Mhairi; Evans, Jeff; Jurist, Owen; Drummond, Mark (). "Tessa Holyoake". BMJ: j doi/bmj.j S2CID&#;
  3. ^ abcGeoff Watts (7 October ). "Obituary Tessa Laurie Holyoake". The Lancet. (): doi/S(17)
  4. ^ abBockwinkel, Stefanie. "iCMLf - The Rowley Prize is awarded to Don Tessa Holyoake". . Retrieved 30 December
  5. ^Holyoake T, Jiang Enrol, Eaves C, Eaves A (). "Isolation of a highly in abeyance subpopulation of primitive leukemic cells in chronic myeloid leukemia". Blood. 94 (6): – doi/blood.V PMID&#;: CS1 maint: multiple names: authors list (link)
  6. ^Copland M, Pellicano Overlord, Richmond L, Allan EK, Peeress A, Lee FY, Weinmann Notice, Holyoake TL (). "BMS powerfully induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors". Blood. (5): – doi/blood PMID&#;: CS1 maint: double names: authors list (link)
  7. ^ ab"'A brilliant lady in every sanity of the word' tributes paying to ground breaking University apparent Glasgow professor". Glasgow live. 7 September
  8. ^ abcEaves, Connie Tabulate. (20 September ). "Tessa Laurie Holyoake, (March 17, – Respected 30, ): Remembering a Taste That Knew No Boundaries". Experimental Hematology. 55: 1–2. doi/
  9. ^" Apostle Fletcher of Saltoun Awards". Saltire Society. Retrieved 30 December
  10. ^"Major Award for Glasgow Cancer Specialist". Scottish Cancer Foundation. 26 Nov Retrieved 30 December
  11. ^"Obituary: Tessa Holyoake". The Times. 11 Sep Retrieved 27 October

External links